GWC Technologies 505 S. Rosa Rd Madison, WI 53719 USA  608.441.2726	SPR IMAGING Surface plasmon resonance (SPR) is a well-established technology for detection of surface interactions. SPR is attractive because it is quantitative and capable of reporting measurements in real time. Plus, SPR can detect loss of mass from the surface as readily as a gain in mass, so you can monitor both association and dissociation events. SPR is label-free For life science research, the fact that SPR works without labels limits artefacts that can arise when biomolecules, especially proteins, are chemically modified with a fluorescent or other tag. However, traditional SPR instruments measure interactions one at a time, multiplexing by adding parallel channels that can be monitored simultaneously. As a result, experimental variation can arise between different samples. SPR imaging detects interactions on arrays To eliminate channel-to-channel variability, and to improve multiplexing capabilities, GWC Technologies offers SPR imaging systems. Instead of monitoring interactions in separate channels, GWC’s SPRimager®II system monitors an entire array of samples in a single flow cell, with all samples exposed to the same analyte solution. This approach: Eliminates channel-to-channel variability Lets you monitor positive and negative control samples at the same time and under the same conditions as experimental samples Improves multiplexing capabilities The SPRimager®II generates both image and graphical data The SPRimager®II system collects image data for arrays, so you have the priceless advantage of using one of your most sophisticated tools—your eyes—to assess your results. Plus, quantitative data are transferred to spreadsheets for numerical analysis. You can plot graphical data for your arrays during data collection, so you can monitor experimental progress and adjust your conditions on the fly if necessary. You can view an example of how interactions on arrays are monitored by watching this 5MB movie. Background information on SPR imaging For more information about how SPR imaging works, please refer to our technical note or contact . ©2008 GWC Technologies Contact our with any questions or comments.